The word affectations is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 22
Highest Scoring Words With Friends™ Play In The Letters affectations
:
Seven Letter Word Alert: (40 words)
aconite, actants, actions, affects, affiant, affines, atonias, atonics, attains, caftans, castoff, cations, coffins, confits, contest, costate, faction, fanatic, fancies, fattens, fatties, fiances, infects, instate, nictate, notices, octanes, octants, offices, offsite, satanic, satiate, section, statice, station, stiffen, taffeta, taffies, tetanic, toffies