The word vacuolations is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 22
Highest Scoring Words With Friends™ Play In The Letters
Seven Letter Word Alert: (31 words)
actions, actuals, alicant, atonias, atonics, auction, canulas, cations, caution, coastal, consult, coolant, lotions, lunatic, nautica, oculist, oilcans, outsail, ovation, satanic, stoical, suction, sultana, toucans, unclots, uncoils, unstoic, valiant, victual, volcano, voltaic