The word toilsomeness is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 17
Highest Scoring Words With Friends™ Play In The Letters toilsomeness
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Seven Letter Word Alert: (56 words)
emotion, enlists, insoles, lenites, lesions, lessens, lessons, lioness, lionets, listens, loonies, loosens, loosest, lotions, meioses, mitoses, moisten, molests, moonlit, motions, nemesis, nestles, netless, noisome, nosiest, oleosin, omelets, onetime, oolites, osmosis, osseins, osselet, osteons, seitens, sessile, session, sestine, siemens, silents, sinless, soloist, someone, somites, somonis, sonless, soonest, stenose, stomies, stoolie, tensile, tieless, tinsels, toeless, tonsils, toolmen, toonies