The word telencephalon is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 25
Highest Scoring Words With Friends™ Play In The Letters telencephalon
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Seven Letter Word Alert: (30 words)
acetone, canteen, channel, chaplet, cheapen, chelate, cholate, collate, echelon, enchant, enhance, enolate, epochal, ethanol, heeltap, hellcat, heptane, heptene, lactone, neonate, nepotal, nonlate, nonleap, penance, pentane, pentene, phenate, polecat, potheen, taphole