The word sextillions is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 21
Highest Scoring Words With Friends™ Plays In The Letters sextillions
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Seven Letter Word Alert: (25 words)
elision, enlists, extolls, illites, illness, inosite, insoles, instill, iolites, ionises, lentils, lesions, lintels, lioness, lionets, lionise, listens, nosiest, oiliest, sextons, silents, sixties, stollen, tinsels, tonsils