The word quadriplegic is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 32
Highest Scoring Words With Friends™ Plays In The Letters
Seven Letter Word Alert: (27 words)
acquire, aedilic, auricle, caliper, calqued, calquer, cliqued, decrial, deliria, earplug, gaudier, glacier, gracile, guilder, icepail, lacquer, lipread, pelagic, plagued, predial, pudgier, quadric, quailed, radicel, radicle, replica, upgrade