The word ineffectuality is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 28
Highest Scoring Words With Friends™ Play In The Letters ineffectuality
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Seven Letter Word Alert: (46 words)
acetify, acutely, afflict, cattily, cauline, ciliate, cuneate, cutleaf, cutline, cyanite, entitle, eyelift, faculty, faintly, fancify, fancily, fateful, fiancee, fifteen, filiate, flatten, fluency, futiley, inflate, inflect, inflict, latency, lattice, lettuce, leucine, leucite, lineate, lunatic, nattily, nictate, niftily, tacitly, tactful, tactile, tailfin, tetanic, titanic, tuftily, unfitly, unleafy, utility