"exacerbation" in the noun sense
1. aggravation, exacerbation
action that makes a problem or a disease (or its symptoms) worse
"the aggravation of her condition resulted from lack of care"
2. exacerbation
violent and bitter exasperation
"his foolishness was followed by an exacerbation of their quarrel"
Source: WordNet® (An amazing lexical database of English)
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