The word disapproves is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 22
Highest Scoring Words With Friends™ Plays In The Letters
Seven Letter Word Alert: (47 words)
adipose, adviser, advises, advisor, apposed, apposer, apposes, apprise, approve, aspired, aspires, avoider, dappers, despair, devisor, diapers, dippers, dispose, dossier, epipods, oppress, ovaries, paresis, passive, peapods, periods, praised, praises, prepaid, provide, roadies, sappers, sappier, saviors, savored, sippers, soapers, soapier, soppers, soppier, spaders, spiders, spireas, spreads, vapider, vapored, voiders