The word disapprobation is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 25
Highest Scoring Words With Friends™ Plays In The Letters
Seven Letter Word Alert: (67 words)
abators, abraids, abstain, adaptor, airboat, anapsid, appoint, artisan, aspirin, astroid, atonias, atropia, bandito, bandits, barista, bastion, batoids, biodots, biotins, bradoon, diarist, disroot, donairs, dopants, inboard, indoors, inroads, isodont, obtains, odorant, onboard, opioids, options, oration, ordains, pardons, parotid, parsnip, patinas, patrons, pianist, piarist, portion, potions, protons, radians, radiant, rations, ripstop, sandbar, sandpit, sopaipa, soprano, spartan, spionid, spiroid, sporont, tapirid, tarpans, tobiano, topspin, tornado, toroids, torpids, torsion, tripods, tsarina