The word determinisms is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 20
Highest Scoring Words With Friends™ Play In The Letters
Seven Letter Word Alert: (88 words)
deities, dements, demerit, demises, demists, deniers, densest, deserts, desires, dessert, destine, diester, dieters, dieties, dietine, dimeter, dimmers, dimmest, dimness, dirties, dissent, ditsier, entries, immense, immerse, inditer, indites, inserts, insider, insides, interim, itemise, menders, merited, messier, metrise, midterm, mimesis, minders, mindset, minters, mintier, misdeem, misedit, misters, mistier, mistime, mitered, nemesis, nesters, nitride, redness, reedits, reemits, remends, reminds, remined, remines, remints, renests, resends, resents, resides, restems, retimed, retimes, seitens, senders, sestine, siemens, simmers, sinters, smiters, snidest, stemmed, sterned, stimied, stimies, strides, tenders, termini, tidiers, timider, tinders, tressed, tridems, trienes, trimmed