The word depressurised is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 19
Highest Scoring Words With Friends™ Play In The Letters
Seven Letter Word Alert: (55 words)
depress, depside, derider, derides, derries, deseeds, desired, desirer, desires, despise, disused, dressed, dresser, dresses, dressup, issuers, perused, peruses, preside, pressed, presser, presses, pursers, pussier, pussies, redress, redried, redries, reedier, reissue, repress, reprise, reseeds, resided, resider, resides, residue, respire, rudders, ruddier, ruddies, seeders, seedier, seepier, speeded, speeder, spiders, spurred, sudsers, sudsier, supered, suspire, upriser, uprises, upsides