The word degenerative is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 20
Highest Scoring Words With Friends™ Play In The Letters
Seven Letter Word Alert: (58 words)
angered, arenite, avenged, avenger, averted, darting, deaving, deraign, derange, deterge, detrain, deviant, deviate, diverge, dragnet, engrave, enraged, entered, evading, everted, evident, grained, granite, granted, grantee, greaten, greened, greeted, grenade, grieved, ingrate, integer, invader, needier, negated, reading, reagent, reaving, reeving, reigned, reneged, revenge, riveted, tangier, tearing, teenage, teenier, tradein, trading, trained, trainee, treeing, triaene, vearing, veering, veteran, vinegar, vintage