The word toothbrushes is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 20
Highest Scoring Words With Friends™ Play In The Letters toothbrushes
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Seven Letter Word Alert: (38 words)
besorts, betroth, booster, booters, bothers, brushes, busters, butters, estrous, herbous, hotshot, hottubs, hushers, obtuser, oestrus, ousters, outbets, outsets, outshot, reboost, reboots, reshoot, shooter, shouter, shutter, soother, soothes, sorbets, sourest, stouter, strobes, subsort, subtest, thrusts, tooters, toruses, touters, turbots