The word mononucleate is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 22
Highest Scoring Words With Friends™ Play In The Letters
Seven Letter Word Alert: (38 words)
acetone, anemone, annulet, calumet, cannolo, canteen, clement, coalmen, connote, coolant, cuneate, elocute, emulant, emulate, enolate, lactone, leucoma, monocle, montane, neonate, noncola, noncute, nonlate, nonmale, nonmate, nonmeal, nonmeat, nonmute, nucleon, nutmeal, outcome, telecom, toluene, toolman, toolmen, unclean, uneaten, unmeant