The word isolationistic is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 19
Highest Scoring Words With Friends™ Play In The Letters isolationistic
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Seven Letter Word Alert: (38 words)
actions, altoist, atonics, caisson, casinos, cassoon, cations, colitis, colossi, consist, coolant, cottons, iconist, initial, italics, liaison, lotions, nicosia, notists, octants, oilcans, oncosis, oolitic, saloons, silicas, silicon, socials, solicit, soloist, stanols, statics, statins, station, stoical, taoists, titanic, tocsins, tonsils