The word guiltlessness is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 19
Highest Scoring Words With Friends™ Play In The Letters
Seven Letter Word Alert: (60 words)
elegist, elegits, eluents, eluting, enlists, ensuite, genesis, gentile, gentles, genuses, glisten, gluiest, glutens, guesses, gullets, gullies, gunless, gussets, gussies, gutless, illness, ingests, insults, legless, lenites, lentils, lessens, lintels, listens, luniest, lusting, nestles, netless, seitens, selling, sessile, sestine, signees, signets, silents, singles, singlet, sinless, sinuses, sullies, sunless, sunsets, tellies, telling, tensile, tieless, tingles, tinsels, tissues, tugless, tussles, ugliest, unlists, useless, utensil