The word enigmatically is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 26
Highest Scoring Words With Friends™ Plays In The Letters enigmatically
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Seven Letter Word Alert: (82 words)
aclinal, acylate, agatine, agilely, agility, ailment, alginic, alicant, aliment, alltime, allying, amenity, amentia, anaemic, analyte, angelic, animacy, animate, anytime, calling, calming, ceiling, celling, ciliate, cleanly, climate, cyanate, cyanite, elating, emacity, gallant, gallate, gametic, gateman, gelatin, geminal, genital, glacial, glycine, gmelina, imagine, intagli, lacinia, lacteal, laminae, laminal, latency, laytime, lignite, lilting, limelit, magenta, magical, magnate, mailing, malting, manacle, mangily, manilla, meatily, melting, metical, micella, milling, miniate, mintage, myalgia, myalgic, mycelia, mycetal, nametag, nematic, netmail, tagline, tailing, teaming, telling, tillage, tilling, yealing, yelling, yelming