The word affirmatives is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 25
Highest Scoring Words With Friends™ Plays In The Letters affirmatives
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Seven Letter Word Alert: (28 words)
affairs, affirms, airiest, airtime, amritas, atavism, atresia, aviates, fairest, fairies, fifties, firmest, irisate, mastiff, misaver, misfire, mistier, restaff, revisit, siriema, smartie, staffer, stiffer, stivier, taffies, tariffs, variate, veritas