The word disaffirmation is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 25
Highest Scoring Words With Friends™ Plays In The Letters disaffirmation
:
Seven Letter Word Alert: (52 words)
affairs, affiant, affirms, affords, affront, amritas, animist, artisan, artsman, astroid, atonias, diarist, diatoms, diorama, diosmin, domains, domatia, donairs, dormant, farmost, forints, formats, indraft, informs, inroads, insofar, mantras, marinas, martian, martini, martins, mastiff, mastoid, matador, matrons, midairs, midriff, mordant, nimrods, oarsman, ordains, radians, radiant, randoms, rations, roadman, saffron, stamina, stardom, tariffs, trifids, tsarina