The word disorganising is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 20
Highest Scoring Words With Friends™ Play In The Letters
Seven Letter Word Alert: (47 words)
adoring, airings, andiron, angioid, arising, darning, dinging, dissing, donairs, dragons, droning, gaining, gassing, girding, girning, goading, grading, indians, indigos, ingrain, innards, inroads, ironing, ordains, origins, raiding, raining, raising, raisins, ranging, ridging, ridings, ringing, rinsing, risings, roaning, sanding, sidings, signing, signora, signors, singing, sinoids, snaring, snoring, soaring, sringas