The word cardiovascular is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 27
Highest Scoring Words With Friends™ Play In The Letters cardiovascular
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Seven Letter Word Alert: (41 words)
acacias, acaudal, accords, accrual, accusal, acicula, acrasid, advisor, ardours, arousal, arrival, ascarid, auroral, auroras, calicos, caloric, cardiac, carload, cicadas, cloacas, cordial, corrals, corsair, crucial, curacao, curials, lauroid, occular, oculars, oscular, radials, radical, radular, radulas, railcar, rosalic, saviour, scoriac, variola, various, vocalic