A man used to vicissitudes is not easily dejected. [ Johnson ]

Vicissitudes of fortune, which spare neither man nor the proudest of his works, which bury empires and cities in a common grave. [ Gibbon ]

Happy is the man who can endure the highest and the lowest fortune. He who has endured such vicissitudes with equanimity has deprived misfortune of its power. [ Seneca ]

Those who have arrived at any very eminent degree of excellence in the practice of an art or profession have commonly been actuated by a species of enthusiasm in their pursuit of it. They have kept one object in view amidst all the vicissitudes of time and fortune. [ John Knox ]

The dramatist, like the poet, is born, not made. There must be inspiration back of all true and permanent art, dramatic or otherwise, and art is universal: there is nothing national about it. Its field is humanity, and it takes in all the world; nor does anything else afford the refuge that is provided by it from all troubles and all the vicissitudes of life. [ William Winter ]

Surely no man can reflect, without wonder, upon the vicissitudes of human life arising from causes in the highest degree accidental and trifling. If you trace the necessary concatenation of human events a very little way back, you may perhaps discover that a person's very going in or out of a door has been the means of coloring with misery or happiness the remaining current of his life. [ Lord Greville ]

With whatever respect and admiration a child may regard a father, whose example has called forth his energies, and animated him in his various pursuits, he turns with greater affection and intenser love to a kind-hearted mother; the same emotion follows him through life; and when the changing vicissitudes of after years have removed his parents from him, seldom does the remembrance of his mother occur to his mind, unaccompanied by the most affectionate recollections. Show me a man, though his brow be furrowed, and his hair grey, who has forgotten his mother, and I shall suspect that something is going on wrong within him; either his memory is impaired, or a hard heart is beating in his bosom. [ Mogridge ]