The word respectfully is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 26
Highest Scoring Words With Friends™ Plays In The Letters respectfully
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Seven Letter Word Alert: (62 words)
cluster, cruelly, cruelty, curtsey, cutlery, ectypes, erectly, eustely, eustyle, eyecups, eyefuls, fellers, fellest, fleetly, fluster, fluters, fuelers, fueller, fullers, fullest, lecture, pellets, pelters, perfect, perfuse, petrels, precuts, prefect, prelect, presell, pullers, pullets, pulleys, purfles, putrefy, recluse, refects, reflect, refuels, refutes, repulse, respect, respell, respelt, restful, restyle, retells, retypes, scepter, sceptre, scruple, specter, spectre, speller, steeply, stupefy, sutlery, tellers, tersely, treeful, yellers, yelpers