The word poikilothermic is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 30
Highest Scoring Words With Friends™ Play In The Letters poikilothermic
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Seven Letter Word Alert: (58 words)
chomper, chortle, chromel, compile, comport, compote, copilot, crimple, empiric, hemlock, hooklet, hoplite, imperil, implike, implore, itchier, limiter, liriope, loopier, meiotic, milkier, moocher, morphic, motlier, oolitic, pelitic, philter, philtre, pickier, pickler, picrite, pitcher, pithier, pitlike, plookie, polemic, politer, politic, porotic, portico, pothole, potiche, precook, precool, prickle, promote, prootic, repilot, repitch, thermic, thicker, tickler, toplike, tremolo, trickie, trickle, tripole, trophic