The word anastomotic is playable in Words With Friends™, no blanks required. Because it is longer than 7 letters, you would have to play off an existing word or do it in several moves.
Words With Friends™ Letter Score: 18
Highest Scoring Words With Friends™ Play In The Letters anastomotic
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Seven Letter Word Alert: (25 words)
actants, actions, atomics, atonias, atonics, attains, cations, catmint, coatman, cottons, maniacs, masonic, motions, octants, osmotic, ottoman, satanic, scatoma, scotoma, somatic, stamina, station, stomata, tomatos, tomcats